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作者报导纽约神经病学院1952年以来连续收治的118例髓母细胞瘤患者,联系此瘤“复发的危险期”的概念进行了分析,并对有关此瘤的治疗和影响生存的其他因素进行了调查。关于胚胎性肿瘤“复发的危险期”的概念,系由Collins等对肾胚胎瘤以公式表明,其假设是,先天性肿瘤复发的危险期等于发病时的年龄加9个月妊娠时间。构成这种假定,乃由于一种胚胎起源的肿瘤要在一定时间之后才会显现出来,这取决于其固有的生长速度(每一种肿瘤的生物学常数)。所以,治疗后残存的瘤细胞得在与前相同的时间内又会增
The authors report that 118 patients with medulloblastoma, who were consecutively admitted to the New York Academy of Neurology since 1952, were analyzed in connection with the concept of “a risk of relapse” and to investigate the treatment of this tumor and other factors that influence survival . The concept of “at risk of relapse” in embryonal tumors is formulated by Collins et al. In the form of a formula for renal embryomas on the assumption that the risk of congenital tumor recurrence is equal to the age of onset plus 9 months of gestation. This assumption is made because a tumor of embryonic origin does not show up until some time later, depending on its inherent growth rate (the biological constant of each tumor). Therefore, after treatment, the remaining tumor cells in the same time with the former will increase