论文部分内容阅读
目的观察准分子激光原位角膜磨镶术(LASIK)和准分子激光上皮下角膜磨镶术(LASEK)术后角膜上皮基底膜下神经分布及形态学特征。方法共焦显微镜观察低、中度近视LASIK及LASEK27例(54眼),术前、术后1、3、6月的角膜上皮基底膜下神经纤维分布和形态学特征,并测定泪膜破裂时间(BUT)和泪液分泌量(SchirmerI值)。结果LASIK(12例,24眼)与LASEK(15例,30眼)术后角膜上皮基底膜下神经纤维的再生和形态学在各时间点差异均无统计学意义。两组中BUT有统计学意义(P<0.05)而SchirmerI值无统计学意义(P>0.05)。结论对于低、中度近视而言,LASIK与LASEK术后角膜上皮基底膜下神经纤维的再生未显示形态学上的差异。
Objective To observe the distribution and morphological features of corneal epithelium under basement membrane after laser in situ keratomileusis (LASIK) and excimer laser epithelial keratomileusis (LASEK). Methods Confocal microscopy was used to observe the distribution and morphologic features of corneal epithelial subepidermal nerve fibers in 27 cases of low and moderate myopia LASIK, 27 cases of LASEK (54 eyes), preoperative and postoperative 1, 3 and 6 months, and the tear film rupture time (BUT) and tear secretion (SchirmerI value). Results There was no significant difference in the regeneration and morphology of corneal epithelial subfascial nerve fibers between LASIK (12 cases, 24 eyes) and LASEK (15 eyes, 30 eyes) at all time points. BUT in both groups was statistically significant (P <0.05) and SchirmerI values were not statistically significant (P> 0.05). Conclusions For LASIK and LASEK, the regeneration of corneal epithelial subfascial nerve fibers did not show morphological differences for low and moderate myopia.