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应用免疫组化SP法 ,通过纤支镜取材或刷片研究肺癌及肺良性病的nm2 3蛋白表达情况 ,以探索nm2 3在肺癌中与肺门或纵隔淋巴结转移的关系 .结果 :肺癌组nm2 3蛋白阳性率低于肺良性病组(P <0 0 5) ,肺癌组肺门或纵隔淋巴结转移的nm2 3蛋白阳性率低于无淋巴结转移组 (P <0 0 5) .表明 :nm2 3蛋白的表达可为术前肺癌有无肺门或纵隔淋巴结转移的参考指标 .
Immunohistochemical SP method was used to study the expression of nm23 protein in lung cancer and benign lung disease by using bronchoscope or brush to explore the relationship between nm23 in lung cancer and hilar or mediastinal lymph node metastasis. Results: Lung cancer group nm2 3 The protein positive rate was lower in the benign lung disease group (P < 0.05), and the positive rate of nm23 protein in lung cancer or mediastinal lymph node metastasis was lower in the lung cancer group than in the no lymph node metastasis group (P <0 05). The expression of protein can be used as a reference index for the preoperative lung cancer with or without mediastinal lymph node metastasis.