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利用折光率的测定,能迅速計算溶液的濃度,药房快速分析法中已經採用,可以达到实际所需要的准确度。等曾于20℃測定了氯化鈉等药品折光率因数(即溶液濃度升高1%折光率的增加数,应用时根据需要測得該种溶液的折光率及水的折光率和折光率因数,即可求出該种溶液的濃度x=(n-n_0)/F)。苏联“药剂与浓溶液的分析”一書中載有1—20%氯化鈉溶液的折光率表,因未註明在何种温度下組成此表,也沒交待在不同温度下如何使用,在使用上有一定的困难。一般物質的折光率是指在20℃测定者。当一种溶液在不同温度下测定將有显著的差異,如药局無恒温設备,採用“药剂与濃溶液的分析”書中1—20%氯化鈉溶液折光率表,必有一定程度的差異。茲欲保証药品溶液含量的准确性;而对治疗有一定的效果,特別是在配制氯化鈉的等滲溶液(0.9%)其含量須准确。作者于20℃附近不同温度情况下,分別測定1—20%及0.5—1.5%氯化鈉液的折光率,求出其溶液濃度与折光率变化的关系。
The use of refractive index measurement can quickly calculate the concentration of the solution, pharmacy has been used in rapid analysis, you can achieve the actual accuracy you need. Had measured the refractive index of sodium chloride and other drugs at 20 ℃ (ie, increase the concentration of the solution 1% increase in the refractive index, the application of the solution as needed, the refractive index of the solution and the water refractive index and refractive index , You can find the concentration of this solution x = (n-n_0) / F). The Soviet Union, “Analysis of Pharmacy and Concentrated Solution,” contains a table of refractive index of 1-20% sodium chloride solution, because it does not indicate at what temperature the composition of this table, did not explain how to use at different temperatures , In the use of certain difficulties. The refractive index of a normal substance means the person who measured at 20 degreeC. When a solution measured at different temperatures will have significant differences, such as pharmacy without constant temperature equipment, the use of “medicine and concentrated solution analysis ” book 1-20% sodium chloride solution refractive index table, there must be A certain degree of difference. We want to ensure the accuracy of drug solution content; while the treatment has a certain effect, especially in the preparation of isotonic sodium chloride solution (0.9%) its content must be accurate. The authors measured the refractive index of 1-20% and 0.5-1.5% sodium chloride solution at different temperatures around 20 ℃, and obtained the relationship between the solution concentration and the refractive index change.