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AIM: To evaluate the possible association between alcohol consumption and Barrett’s esophagus(BE).METHODS: We performed a systematic literature search of multiple online electronic databases.Inclusion criteria entailed studies about alcohol and BE.Metaanalysis was conducted to evaluate odds ratio(OR) and95%CIs for the association between alcohol consumption and BE.RESULTS: Twenty studies comprising 4758 patients with BE were included in the meta-analysis.The risk of BE in patients with alcohol consumption was increasedcompared with control groups(OR = 1.01; 95%CI: 1.00-1.02),especially in case-control and cohort,European and Asian,and hospital studies,but there was a decreased risk of BE associated with alcohol consumption from American studies(OR = 0.86; 95%CI: 0.77-0.96).At the same time,there was no significant association between BE and alcohol consumption in community studies(OR = 0.97; 95%CI: 0.84-1.12) and the type of alcohol(wine,beer and liquor) studies.CONCLUSION: Our meta-analysis found that alcohol consumption was associated with an increased risk of BE,especially for European and Asian drinkers.
AIM: To evaluate the possible association between alcohol consumption and Barrett’s esophagus (BE). METHODS: We performed a systematic literature search of multiple online electronic databases. Inclusion criteria entailed studies about alcohol and BE. Metanalysis was conducted to evaluate odds ratio (OR) and95% CIs for the association between alcohol consumption and BE.RESULTS: Twenty studies comprising 4758 patients with BE were included in the meta-analysis. The risk of BE in patients with alcohol consumption was increasedcompared with control groups (OR = 1.01; 95% CI: 1.00-1.02), especially in case-control and cohort, European and Asian, and hospital studies, but there was a decreased risk of BE associated with alcohol consumption from American studies (OR = 0.86; 95% CI: 0.77-0.96 ) .At the same time, there was no significant association between BE and alcohol consumption in community studies (OR = 0.97; 95% CI: 0.84-1.12) and the type of alcohol (wine, beer and liquor) studies.CONCLUSION: Our meta-an alysis found that alcohol consumption was associated with an increased risk of BE, especially for European and Asian drinkers.