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目的探讨幽门螺旋杆菌(Helicdbacter pylori,H.Pylori)感染与巨幼细胞贫血(megaloblastic anemia)患儿之间的关系。方法以2005年2月至2010年10月在我院就诊的137例巨幼细胞贫血患儿为实验组,随机统计102例健康查体儿童为对照组,分别用胶体金方法进行血清幽门螺旋杆菌抗体检测。结果实验组幽门螺旋杆菌抗体阳性69例(50.36%),对照组幽门螺旋杆菌抗体阳性23例(22.54%),实验组和对照组阳性率比较差异具有统计学意义(P<0.05)。结论 H.Pylori与MA之间具有显著的相关性,临床治疗MA同时应根除H.Pylori。
Objective To investigate the relationship between Helicobacter pylori (H. pylori) infection and children with megaloblastic anemia. Methods A total of 137 children with megaloblastic anemia treated in our hospital from February 2005 to October 2010 were selected as experimental group and 102 healthy children as control group were randomly divided into control group and colloid gold method respectively for serum Helicobacter pylori Antibody detection. Results The positive rate of H. pylori was 69.3% (50.36%) in the experimental group and 23 (22.54%) were H. pylori positive in the control group. There was significant difference between the experimental group and the control group (P <0.05). Conclusions There is a significant correlation between H.Pylori and MA. Clinical treatment of MA should eradicate H.Pylori.