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目的:研究常规高频超声与超声弹性成像在甲状腺结节良恶性鉴别诊断中的应用价值。方法:选择住院的甲状腺结节性疾病患者120例(146个甲状腺结节)。对患者进行常规高频超声和超声弹性成像检查,以术后病理检查为金标准,计算不同方法对甲状腺良恶性结节鉴别诊断的灵敏度、特异度、准确度。结果:120例患者,经手术病理检查证实有146个结节,其中良性结节98个,恶性结节48个。常规高频超声显示在形态、边界、包膜、内部回声、微钙化及RI值上,甲状腺良、恶性结节之间的差异有统计学意义(P<0.05)。常规高频超声与弹性成像相比,诊断效能之间的差异无统计学意义(P>0.05);常规高频超声与联合超声诊断的灵敏度(X~2=12.22,P<0.01)、特异度(X~2=10.21,P<0.01)、准确度(X~2=9.31,P<0.01)相比较,差异具有统计学显著性;超声弹性成像与联合超声诊断灵敏度(X~2=6.51,P<0.01)、特异度(X~2=5.82,P<0.05)、准确度(X~2=4.56,P<0.05)相比,差异具有统计学显著性。结论:常规高频超声联合超声弹性成像对甲状腺良恶性结节的诊断灵敏度和准确度高,值得进一步推广临床应用。
Objective: To study the value of routine high-frequency ultrasound and ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. Methods: 120 patients with thyroid nodular disease (146 thyroid nodules) were selected for hospitalization. The patients underwent routine high-frequency ultrasound and ultrasound elastography examination, postoperative pathological examination as the gold standard, calculate the sensitivity, specificity and accuracy of different methods for the differential diagnosis of benign and malignant thyroid nodules. Results: Of the 120 patients, 146 nodules were confirmed by operation and pathology, including 98 benign nodules and 48 malignant nodules. Conventional high-frequency ultrasound showed significant differences between benign and malignant thyroid nodules in morphology, border, envelope, internal echo, microcalcifications and RI (P <0.05). There was no significant difference in diagnostic efficacy between conventional high-frequency ultrasound and elastography (P> 0.05). The sensitivity of conventional high-frequency ultrasound and combined ultrasound (X ~ 2 = 12.22, P <0.01) (X ~ 2 = 10.21, P <0.01), accuracy (X ~ 2 = 9.31, P <0.01) .The difference between the two groups was statistically significant. P <0.01), specificity (X ~ 2 = 5.82, P <0.05), accuracy (X ~ 2 = 4.56, P <0.05). Conclusion: The diagnostic sensitivity and accuracy of conventional high-frequency ultrasound and ultrasound elastography in the diagnosis of benign and malignant thyroid nodules are high, which is worth further promotion of clinical application.