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目的分析口腔舒合剂对于神经危重症患者口腔溃疡和感染的防治效果,为临床重症患者口腔溃疡和感染的防治提供新的方法。方法选取2015年7月—2016年4月入住某医院神经危重症加强治疗病房住院时间超过4d的患者,2015年7—11月的患者为口腔溃疡和感染的常规防治组,使用生理盐水进行口腔的常规护理防治;2015年12月—2016年4月的患者为口腔舒合剂防治组,使用按中药组方煎制而成的口腔舒合剂进行防治。均连续5d为一疗程。二组均于入院当天开始每天进行口腔溃疡和感染的临床状态评价。根据患者口腔黏膜有无溃疡、出血或水肿等情况评估口腔护理的效果。结果在收治的患者中常规治疗组74例,口腔舒防治组77例。口腔舒合剂防治组的临床显效率和有效率均明显高于常规防治组(χ~2=9.657、P=0.008),总有效率也明显高于常规防治组(80.5%、59.5%,χ~2=8.000、P=0.007)。结论口腔舒合剂对于神经危重症患者口腔溃疡和感染具有较好的防治效果,但应对影响其疗效的相关因素进行更深入地研究。
Objective To analyze the preventive and therapeutic effects of Oral Shuangji on oral ulcer and infection in critically ill patients with neurological diseases and to provide a new method for the prevention and treatment of oral ulcer and infection in critically ill patients. Methods From July 2015 to April 2016, patients admitted to a hospital with neurological critical illness and intensive care unit for more than 4 days were selected. Patients in July-November 2015 were treated with conventional oral ulcer and infection control group. Of the conventional care and prevention and treatment; December 2015 - April 2016 patients with oral Shu agent control group, the use of traditional Chinese medicine prescriptions made of oral Shu Shu agent for prevention and treatment. Continuous 5d for a course of treatment. Both groups began daily oral ulcer and infection clinical evaluation. According to the patient’s oral mucosa with or without ulcers, bleeding or edema assessment of the effect of oral care. Results Among the patients treated, 74 cases were treated with conventional therapy and 77 cases were treated with oral Shu control. The effective rate and effective rate of oral Shujiu mixture in prevention and treatment group were significantly higher than those in control group (χ ~ 2 = 9.657, P = 0.008). The total effective rate was also significantly higher than that in conventional prevention group (80.5%, 59.5% 2 = 8.000, P = 0.007). Conclusion Oral Shu Aikang has good preventive and therapeutic effects on oral ulcer and infection in critically ill patients with neurological diseases. However, the related factors affecting its curative effect should be studied in more depth.