溶菌酶可使某些细菌(如微球菌等)的细胞壁溶解,其作用机制系催化细胞壁的粘多糖成分N-乙酰粘质酸和N-乙酰氨基葡萄糖之间的β-(1-4)糖苷犍发生水解。因此,亦称为粘质酸酶(Muramidase)。在中性粒细胞,单核细胞和原始单核细胞中含有此酶,而淋巴细胞中没有这种酶。血清中的溶菌酶主要来自中性粒细胞和单核细胞。1966年Osserman等报告急性单核细胞性白血病患者的血清和尿中出现大量溶菌酶,此后许多工作说明白血病患者的溶菌酶测定具有一 Lysozyme can dissolve the cell wall of certain bacteria (such as Micrococcus, etc.), the mechanism of action of which is to catalyze the β- (1-4) glycoside between N-acetylhomocysteine ​​and N-acetylglucosamine in the cell wall’s mucopolysaccharide犍 Hydrolysis occurs. Therefore, also known as muramidase (Muramidase). This enzyme is present in neutrophils, monocytes and primate monocytes, but not in lymphocytes. Serum lysozyme mainly from neutrophils and monocytes. In 1966, Osserman et al. Reported a large amount of lysozyme in the serum and urine of patients with acute monocytic leukemia. Since then, many studies have shown that lysozyme assay in patients with leukemia has one