报告1例长入小脑脑桥角的颅底孤立性浆细胞瘤。在患者的脑脊液中检出了异常蛋白(即和骨髓瘤同一的Lambda型轻链蛋白)。本文讨论了颅底孤立性浆细胞瘤与此部位的其他肿瘤,如脊索瘤和脑膜瘤在鉴别上的困难(情况)。浆细胞瘤侵犯颅,尤其侵犯颅的穹窿是周知的,但伴有颅神经麻痹的颅底浆细胞瘤是罕见的。病例报告:这个28岁男性,入院前8个月枕部头痛,入院前2个月步态不稳和咽下困 Report 1 cases of growth into the cerebellar pontine solitary skull base solitary plasmacytoma. Abnormal protein (ie, the same Lambda-type light chain protein as myeloma) was detected in the patient’s cerebrospinal fluid. This article discusses the differential diagnosis of skull base solitary plasmacytoma with other tumors at this site, such as chordoma and meningiomas. Plasmacytoma invasion of the skull, especially the violation of the cranial culdum is well known, but with cranial nerve palsy of the skull plasmacytoma is rare. Case Report: The 28-year-old man had a occipital headache for the first eight months before admission, unstable gait and swallowing two months before admission