采用佝偻病简易诊断标准和骨碱性磷酸酶(ABLP)测定对194名住院婴幼儿进行佝偻病筛查,同时对59例进行了血钙、磷、碱性磷酸酶测定。结果:经临床综合诊断,婴幼儿佝偻病患痛率为73.2％,简易诊断患病率为42.3％,应用BALP测定患病率68％;59例钙、磷、碱性磷酸酶测定.异常率分别为16.9％,11.9％、54.2％。对BALP升高的患儿补充治疗量维生素D后,其降酶有效率为95.7％,说明BALP测定对小儿佝偻病的诊断和疗效判定有较高的临床应用价值。 A total of 194 hospitalized infants were tested for rickets using the simple diagnostic criteria of rickets and bone alkaline phosphatase (ABLP) assay, and serum calcium, phosphorus and alkaline phosphatase levels were measured in 59 patients. Results: The clinical diagnosis of rickets in infants and young children was 73.2%, the rate of simple diagnosis was 42.3%, the prevalence of BALP was 68% and the rate of calcium, phosphorus and alkaline phosphatase was 59. Abnormal rate Respectively, 16.9%, 11.9%, 54.2%. After the treatment of vitamin D supplementation in children with BALP, the effective rate of reducing enzyme was 95.7%, indicating that the determination of BALP in children with rickets diagnosis and efficacy of a higher clinical value.