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目的探讨老年人轻度帕金森病样体征(MPS)发生的危险因素。方法随机选取无明显神经系统疾病的老年人240例,比较伴发MPS(MPS组,64例)与无MPS者(MPS组,176例)患有脑白质损害、静止性脑梗死、糖尿病、高血压、冠心病的差异,logistic多因素回归分析MPS的危险因素。结果MPS组较无MPS组患者的年龄(P<0.05)、出现脑白质损害的比例(P<0.01)及糖尿病的比例(P<0.01)明显增高,logistic多因素回归分析显示,脑白质损害、糖尿病及年龄仍是MPS发生的危险因素。结论MPS是老年人常见的神经系统体征,其发生与脑白质损害、糖尿病有显著关系。
Objective To investigate the risk factors of mild Parkinson’s disease (MPS) in the elderly. Methods A total of 240 elderly patients without obvious neurological diseases were randomly selected. Compared with MPS group (MPS group, 64 cases) and MPS group (176 cases), white matter damage, static cerebral infarction, diabetes, high Blood pressure, coronary heart disease differences, logistic multivariate regression analysis of MPS risk factors. Results Compared with MPS group, the age of MPS group (P <0.05), the percentage of white matter damage (P <0.01) and the proportion of diabetes mellitus (P <0.01) were obviously increased. Logistic regression analysis showed that the white matter damage, Diabetes mellitus and age are still risk factors for MPS. Conclusion MPS is a common neurological signs in the elderly, its occurrence and white matter damage, diabetes have a significant relationship.