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目的 :研究中药注射液在对患者的治疗过程中出现的不良反应的原因和处理,为今后在临床上合理用药提供依据和参考标准。方法 :以2010年1月-2012年1月来我院进行中药注射液的治疗发生不良反应的100例患者为研究对象。观察其临床具体反应和具体用药的处方,总结临床不良反应的具体特点和以后的合理用药的处理策略。结果 :中药注射液引发的主要不良反应包括,皮肤过敏反应、休克反应、肝衰竭、肾衰竭、呼吸系统和消化系统以及心血管系统的损坏等。其中皮肤过敏反应主要占43.29%,肝肾衰竭占12.10%,呼吸系统占6.12%.发生原因主要是医务工作者对中药注射液应用方法和使用剂量的掌握不足、药物成分不确定因素、患者自身体质对药物的拮抗作用。结论 :对于中药注射液的应用,要根据具体情况,观察充分患者的体质和临床具体病情,做到针对性治疗,严格掌握具体的用药方法,规范临床用药的措施,使用正规厂家正规批次生产的中药注射液,降低患者对药物的不良反应。
Objective: To study the causes and treatment of adverse reactions of traditional Chinese medicine injection in the treatment of patients, and to provide the basis and reference standards for the rational use of drugs in the future. Methods: From January 2010 to January 2012 in our hospital for the treatment of traditional Chinese medicine injection of adverse reactions in 100 patients as the research object. To observe the clinical specific reactions and prescriptions for specific medication, summarize the specific characteristics of clinical adverse reactions and the rational treatment strategy. Results: The main adverse reactions caused by traditional Chinese medicine injection include skin allergic reaction, shock reaction, liver failure, renal failure, respiratory and digestive system and cardiovascular system damage. The main skin allergic reactions accounted for 43.29%, liver and kidney failure accounted for 12.10%, respiratory system accounted for 6.12% .The reason is mainly due to medical workers on the Chinese medicine injection method and the dose of inadequate mastery, the drug composition of uncertainties, the patient itself Physical antagonism of the drug. Conclusion: The application of traditional Chinese medicine injections, according to the specific circumstances, to observe the full patient’s physical and clinical specific conditions, so that targeted treatment, strict control of specific methods of medication, regulate clinical medication measures, the use of formal regular batch production Chinese medicine injection to reduce adverse drug reactions in patients.