论文部分内容阅读
建立了一套用于测量生物组织模型偏振后向散射差分光谱的实验系统。在系统中,线偏振光入射到样品表面,检偏器和光谱仪配合记录后向散射光中的平行和垂直分量,随后计算出差分光谱。采用了平均直径分别为5.0μm、9.0μm的两种聚乙烯小球悬浮液进行实验,结果与蒙特卡罗模拟进行对照,验证了实验系统的正确性。初步研究了粒子尺寸分布变化对差分光谱的影响,结果表明,偏振散射差分光谱能敏感地反映粒子尺寸分布的变化,在大小粒子的混合液中,大粒子浓度一定程度的增加,光谱仍保留小粒子的振荡趋势,但差分光强减小。该方法对于早期癌症检测具有潜在应用意义。
A set of experimental system for measuring polarized backscattering difference spectra of biological tissue models was established. In the system, linearly polarized light is incident on the sample surface, and the analyzer and spectrometer cooperate to record the parallel and perpendicular components of the backscattered light, followed by the calculation of the differential spectrum. Two kinds of polyethylene beads suspension with average diameter of 5.0μm and 9.0μm were used respectively. The results were compared with Monte Carlo simulations to verify the correctness of the experimental system. The results show that the polarization dispersion spectrum can reflect the change of particle size distribution sensitively. In the mixed solution of large and small particles, the concentration of large particles increases to a certain degree and the spectrum remains small The oscillation tendency of the particles, but the differential light intensity decreases. This method is potentially useful for early detection of cancer.