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采用ＢＨＫ－２１细胞蚀斑减少中和试验，检测扬中县６～１８月龄婴儿乙型脑炎灭活疫苗中和抗体，追踪调查接种反应和第２年加免前后抗体变化，探讨３针基础免疫效果。结果表明：乙脑基础免疫中和抗体阳转率３针组达８２．２６％，２针组５２．９４％．Ｐ＜０．００５；抗体ＧＭＴ３针组１３．９０，２针组７．５７．Ｐ＜０．００５。第２年抗体维持水平，阳性率３针组７５．００％，２针组５１．５％．Ｐ＜０．００５；抗体ＧＭＴ３针组１１．８７，２针组５．８６，Ｐ＜０．０２。加免后阳性率，３针组达１００％，２针组９７．０６５，Ｐ＞０．５；抗体ＧＭＴ３针组１８８．０９，２针组为５６．１９．Ｐ＜０．００１。接种反应追踪调查未见严重反应，有关指标无组间和注射针次间差异（Ｐ＞０．５）。提示：采用３针进行乙脑疫苗基础免疫是安全的．可供选择的免疫策略。
The BHK-21 cell plaque reduction neutralization test was used to detect neutralizing antibodies against Japanese encephalitis inactivated vaccine of 6-18 month-old infants in Yangzhong County. The vaccination responses were tracked and the antibody changes before and after the second year were investigated. Immune effect. The results showed that the positive rate of neutralizing antibody in JE group was 82.26% in the 3-needle group and 52.94% in the 2-needle group. P <0.005; antibody GMT3 needle group 13.90, needle 2 group 7.57. P <0.005. The first two years of antibody maintenance level, the positive rate of 3 needle group 75.00%, 2 needle group 51.5%. P <0.005; antibody GMT3 needle group 11.87, needle 2 group 5.86, P <0.02. The positive rate after plus and minus was 100% in the 3-stitch group, 97.065 in the 2-stitch group, and P> 0.5. The antibody GMT3 stitch group 188.09 and the 2 st stitch group was 56.19. P <0.001. There was no serious response to the vaccination follow-up survey. There was no significant difference between the two groups (P> 0.5). Tip: The 3-pin JE vaccine based on the immune is safe. Alternative immunization strategies.