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目的 :了解应用甲基强的松龙注射剂SARS患者的病情、治疗情况和不良反应。方法 :回顾性分析小汤山医院临床确诊的 6 80例SARS患者的病案、用药记录及药品不良反应发生情况 ,将其分为应用和未用甲基强的松龙注射剂 2组 ,描述性分析两组病例基本病情和不良反应。结果 :使用甲基强的松龙注射剂患者的病情程度较未使用甲基强的松龙注射剂的患者严重 ,平均服用药品种类也较多 ;使用甲基强的松龙注射剂患者的药品不良反应 (ADR)发生率要高于未使用甲基强的松龙注射剂患者 ,发现该组病人出现高血糖、低血钾和白细胞升高等药物不良反应。结论 :在SARS治疗过程中需慎重使用甲基强的松龙注射剂 ,严密观察其药物不良反应。
Objective: To understand the condition, treatment and adverse reactions of SARS patients who use methylprednisolone injections. Methods: A retrospective analysis of Xiaotangshan Hospital clinically diagnosed cases of 80 cases of SARS patients, medication records and adverse drug reactions, divided into two groups with and without methylprednisolone injection, descriptive analysis of two Group of patients with the basic condition and adverse reactions. Results: The patients who used methylprednisolone injection were more serious than those who did not use methylprednisolone injection, and the patients taking methylprednisolone injection were more likely to take drugs. The adverse reactions of drugs with methylprednisolone injection ADR) was higher than those who did not use methylprednisolone injections, found that patients in this group of patients with hyperglycemia, hypokalemia and leukocytosis and other adverse drug reactions. Conclusion: Methylprednisolone injection should be carefully used in the treatment of SARS, and its adverse drug reactions should be closely observed.