论文部分内容阅读
目的探讨尿微量白蛋白(U-Alb)和α1-微球蛋白(α1-MG)在糖尿病肾病早期筛查和治疗中的作用。方法测定96例糖尿病患者和93例健康体检者血尿素氮(BuN)、肌酐(Cr)、尿蛋白定性、尿微量白蛋白和α1-微球蛋白并进行分析。结果糖尿病组尿微量白蛋白和α1-微球蛋白的测定结果明显高于健康对照组(P<0.01),具有统计学意义。结论定期进行尿微量白蛋白和α1-微球蛋白的联合检测对糖尿病肾病早期诊断有重要意义。
Objective To investigate the role of urinary albumin (U-Alb) and α1-microglobulin (α1-MG) in early screening and treatment of diabetic nephropathy. Methods The levels of blood urea nitrogen (BuN), creatinine (Cr), urinary protein, urine microalbumin and α1-microglobulin in 96 diabetic patients and 93 healthy controls were measured and analyzed. Results The results of urine microalbumin and α1-microglobulin in diabetic group were significantly higher than those in healthy control group (P <0.01), with statistical significance. Conclusions Regular urine microalbumin and α1-microglobulin combined detection of diabetic nephropathy early diagnosis is important.