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以消化道癌单克隆抗体,用酶免疫──醋酸纤维薄膜电泳法检测消化道癌、非消化道癌、肠炎、正常人粪便中癌相关抗原。结果表明:对应抗原在大肠癌、食管癌、胃癌、贲门癌患者粪便中的平均含量显著高于非消化道癌、肠炎和正常对照组。其阳性率分别为77.63%、57.14%、60%、61.54%、11.53%、11.76%、0,尤其是直肠癌中8例早期(DukesA)患者均为(+)。此法为早期诊断提供了简便可行的新手段。
Using monoclonal antibodies against digestive tract cancer, enzyme-immunity-acetate membrane electrophoresis was used to detect cancer-associated antigens in digestive cancer, non-digestive cancer, enteritis, and normal human feces. The results showed that the average content of corresponding antigen in feces of patients with colorectal cancer, esophageal cancer, gastric cancer, and cardiac cancer was significantly higher than that of non-digestive cancer, enteritis, and normal controls. The positive rates were 77.63%, 57.14%, 60%, 61.54%, 11.53%, 11.76%, 0, respectively, especially in 8 patients with early stage (DukesA) in rectal cancer. +). This method provides a simple and feasible new means for early diagnosis.