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目的分析手术联合化疗在口腔鳞癌中的应用效果。方法回顾性分析濮阳市第三人民医院2012年1月至2014年12月收治的68例口腔鳞癌患者的临床资料,根据不同治疗方案分为两组,每组34例,两组均予以手术治疗,对照组联合常规化疗治疗,研究组联合间质化疗治疗,比较两组临床近期疗效及治疗前后淋巴转移率。结果研究组近期总有效率高于对照组,淋巴转移率低于对照组,差异均有统计学意义(P<0.05)。结论手术联合间质化疗治疗口腔鳞癌可有效降低淋巴转移率,提高临床疗效。
Objective To analyze the application effect of surgery combined with chemotherapy in oral squamous cell carcinoma. Methods The clinical data of 68 cases of oral squamous cell carcinoma in Puyang Third People’s Hospital from January 2012 to December 2014 were retrospectively analyzed. According to the different treatment plans, the patients were divided into two groups (34 cases in each group) The treatment group and the control group were treated with conventional chemotherapy, and the study group was treated with interstitial chemotherapy. The clinical curative effect and lymph node metastasis rate before and after treatment were compared between the two groups. Results The total effective rate of the study group was higher than that of the control group, and the lymph node metastasis rate was lower than that of the control group. The difference was statistically significant (P <0.05). Conclusion Operation combined with interstitial chemotherapy in the treatment of oral squamous cell carcinoma can effectively reduce the lymphatic metastasis rate and improve the clinical curative effect.