[答]青霉素过敏反应和过敏休克的发生,目前尚有些问题没有研究清楚。现已知青霉素特别是它的代谢产物,在机体内与蛋白质形成共价键结合而具有免疫原性,刺激机体免疫机制产生抗体。第二次这种药物再次进入体内,即可发生抗体抗原结合反应(过敏反应)。青霉素及其代谢产物与蛋白质结合所产生的 [A] penicillin allergic reactions and the occurrence of anaphylactic shock, there are still some problems not studied clearly. It is known that penicillin, especially its metabolites, is immunogenic by forming a covalent bond with the protein in the body and stimulating the body’s immune mechanism to produce antibodies. The second time the drug enters the body again, an antibody-antigen binding reaction (anaphylaxis) can occur. Penicillin and its metabolites and proteins produced by the combination