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目的探讨西藏藏族成人骨强度指数的变化特点,并分析骨量异常与体成分的相关性。方法抽取西藏藏族自治区日喀则市藏族成人560例,采用生物电阻抗分析仪及超声骨密度仪分别测量被研究者体成分各指标及右足跟骨骨强度指数、T值等,采用非条件Logistic回归法分析骨量异常与体成分间的关系。结果西藏藏族男女性成人骨强度指数均在18~30岁达到峰值,之后随年龄增长而下降;50岁以上男女性骨质疏松症检出率分别为7.6%及11.7%;Binary Logistic回归分析显示,年龄(B=0.046,OR=1.047,P<0.01)、内脏脂肪量(B=0.452,OR=1.572,P<0.05)是西藏藏族成人发生骨量异常的危险因素,而皮下脂肪含量(B=-0.181,OR=0.835,P<0.01)及肌肉量(B=-0.055,OR=0.947,P<0.05)是骨量异常的保护性因素,腰臀比与骨量异常无相关性。结论西藏藏族50岁以上人群骨质疏松症发病率相对国内其他报道的民族同龄人群较低;内脏脂肪量越高、皮下脂肪量及肌肉量越低者,发生骨量下降及骨质疏松症的危险性越高。
Objective To explore the change characteristics of Tibetan bone strength index in Tibet and to analyze the correlation between bone anomalies and body composition. Methods 560 Tibetan adults in Shigatse were collected from Tibet Autonomous Region. Bioelectrical impedance analyzer and ultrasonic bone density meter were used to measure body composition index and right calcaneus bone strength index and T value respectively. Non-conditional Logistic regression Analysis of the relationship between abnormal bone mass and body composition. Results The Tibetan males and females’ adult bone strength index peaked at 18-30 years of age and then decreased with age. The prevalence of osteoporosis in men and women over 50 years old was 7.6% and 11.7%, respectively. Binary Logistic regression analysis (B = 0.046, OR = 1.047, P <0.01), visceral fat mass (B = 0.452, OR = 1.572, P <0.05) were risk factors for bone anomaly in Tibetan adults in Tibet, = -0.181, OR = 0.835, P <0.01) and muscle mass (B = -0.055, OR = 0.947, P <0.05) were the protective factors of abnormal bone mass. There was no correlation between WHR and bone mass abnormality. Conclusions The prevalence of osteoporosis in Tibetans over 50 years old is lower than that of other ethnic cohorts reported in China. The higher the visceral fat mass is, the lower the amount of subcutaneous fat and muscle mass is, the lower the osteopenia and osteoporosis The more dangerous.