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[目的]探讨影响原始神经外胚层肿瘤预后的相关因素。[方法]回顾性分析了49例原始神经外胚层肿瘤患者的临床资料及预后相关因素。[结果]49例原始神经外胚层肿瘤的1年、2年、3年、5年生存率分别为65.3%、51.0%、26.5%、8.4%、中位生存时间为16个月;单因素分析显示年龄、肿块大小、分期、治疗方式是影响原始神经外胚层肿瘤患者预后的重要因素。Cox多因素分析后发现肿瘤分期和治疗方式是影响其预后的独立危险因素。[结论]原始神经外胚层肿瘤采用联合放疗的综合治疗方案有助于改善患者的预后。
[Objective] To investigate the related factors that affect the prognosis of primitive neuroectodermal tumors. [Methods] The clinical data and prognostic factors of 49 patients with primitive neuroectodermal tumors were retrospectively analyzed. [Results] The 1-, 2-, 3- and 5-year survival rates of 49 primitive neuroectodermal tumors were 65.3%, 51.0%, 26.5% and 8.4%, respectively. The median survival time was 16 months. Univariate analysis Show age, size of the tumor, staging, treatment is an important factor affecting the prognosis of patients with primitive neuroectodermal tumors. Cox multivariate analysis found that tumor staging and treatment are independent prognostic risk factors. [Conclusion] The combination therapy of radiotherapy and primary neuroectodermal tumor can improve the prognosis of patients.