家族性嗜铬细胞瘤比较罕见,我院1987年2月～1997年4月收治3例二代嗜铬细胞瘤,均经手术治愈,现报道如下。例1男,16岁,因阵发性剧烈头痛,头晕,恶心,呕吐,出冷汗二年入院。每次发作持续约数分钟。按高血压治疗无效。体检:体温37℃,脉搏82次/分,呼吸16次/分,血压20/10.7kPa。腹部未扪及肿物,无血管杂音。化验:血、尿常规正常,肝肾功能、血清电解质正常范围,血糖正常范围,24小时VMA98.6毫克。心电图正常。静脉尿路造影无异常改变。B超双肾上腺增大。腹膜后充气造影显示:左、右肾上腺区分别有3.5×4.0厘米,4.0×5.5厘米阴影。组织胺激发试验血压由20/13.3kPa升到37/24kPa,立即注入酚妥拉明后血压降至20.7/ Familial pheochromocytoma is relatively rare, our hospital from February 1987 to April 1997 treated 3 cases of second-generation pheochromocytoma, were cured by surgery, are reported below. Example 1 Male, 16 years old, due to severe paroxysmal headache, dizziness, nausea, vomiting, cold sweat admitted two years. Each episode lasts for about a few minutes. Treatment by hypertension is invalid. Physical examination: body temperature 37 ℃, pulse 82 beats / min, breathing 16 beats / min, blood pressure 20 / 10.7kPa. Abdominal palpable mass, no vascular noise. Laboratory: blood, urine normal, liver and kidney function, serum electrolyte normal range, normal range of blood glucose, 24-hour VMA98.6 mg. Normal ECG. Intravenous urography without abnormal changes. B super adrenal enlargement. Retroperitoneal gasification angiography showed: left and right adrenal area were 3.5 × 4.0 cm, 4.0 × 5.5 cm shadow. Histamine stimulation test blood pressure rose from 20 / 13.3kPa 37 / 24kPa, immediately after injection of phentolamine blood pressure dropped to 20.7 /