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子痫前期是孕期特有的高血压疾病,是发生于妊娠中晚期严重威胁母婴安全的急性并发症,在高血压、蛋白尿基础上,出现头痛、眼花、恶心、呕吐、上腹不适等一系列症候群。子痫是导致孕产妇死亡的重要原因之一,因此在症状出现之前预测该病并采取预防措施,可减轻对母婴危害及并发症的发生,对于该病的防治具有重要的临床意义。文章综述了GRP78(葡萄糖蛋白78)、VEGF(血管内皮生长因子)在子痫前期患者中的研究。
Preeclampsia is a unique hypertensive disorder during pregnancy. It is an acute complication that occurs in the second and third trimester of pregnancy and threatens the safety of mother and infant. One of the main causes of headache, vertigo, nausea, vomiting and abdominal discomfort is found on the basis of hypertension and proteinuria Series syndrome. Eclampsia is one of the important causes of maternal death. Therefore, predicting the disease before the onset of symptoms and taking preventive measures can reduce the harm to maternal and infant and the occurrence of complications, which is of important clinical significance for the prevention and treatment of the disease. The article reviews the studies of GRP78 (glucose protein 78), VEGF (vascular endothelial growth factor) in patients with preeclampsia.