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小鼠口服地偷或虎杖鞣质２０ｍｇ／ｋｇ明显对抗氨基比林（ＡＰ）合并ＮａＮＯ２引起的急性肝损伤。小鼠耳部涂抹地榆或虎杖鞣质４ｍｇ，显著抑制巴豆油诱发的耳部肿胀。口服此两化合物１ｇ／ｋｇ／日，连服４天，也有效抑制巴豆油诱发的耳部肿胀。此两化合物２．５μｇ／ｍｌ明显抑制Ｏ２的产生。６０μｇ／ｍｌ显著对抗Ｈ２Ｏ２诱发的溶血。１６０μｇ／ｍｌ对羟自由基（’ＯＨ）有明显清除作用。
The mice were orally taken orally with 20 mg/kg of Polygonum cuspidatum significantly against acute liver injury caused by aminopyrine (AP) combined with NaNO2. The ear of the mouse was smeared with ground razor clam or 4 kg of Polygonum cuspidatum, which significantly inhibited ear swelling induced by croton oil. Oral administration of these two compounds at 1g/kg/day, for 4 days, also effectively suppressed ear swelling induced by croton oil. The two compounds 2.5 μg/ml significantly inhibited the production of O2. 60 μg/ml significantly counteracts H2O2-induced hemolysis. 160 μg/ml had significant clearance of hydroxyl radical (’OH).