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人们已公认硫化氢中毒是一种职业性毒害至少已有两个世纪了。直至现在还没有找到对硫化物有特异性的解毒剂。一些作者将硫化物中毒和氰化物中毒进行了比较,且发现两者之间有许多类似之处。在实验性动物身上用亚硝酸钠静脉给药所致的医源性正铁血红蛋白血症对硫化物,同样也对氰化物既有保护作用又有解毒作用。这种方法已经成功地用于一部分重症硫化物中毒的病人身上。硫化物中毒引起血氧运输能力的损害是没有根据的。另一方面,某些硫化氢中毒的受害者出现明显的紫绀提示在这种情况下出现呼吸道阻塞较一般地认识更常见。上呼吸道吸引及给氧对用亚硝酸钠的病人来说可能是重要的辅助治疗。
It has been recognized that hydrogen sulfide poisoning is a form of occupational poisoning for at least two centuries. Until now no antidote to sulfide has been found. Some authors have compared sulphide poisoning with cyanide poisoning and found many similarities between the two. In experimental animals with intravenous administration of sodium nitrite iatrogenic methemoglobinemia on the sulfide, also has the protective effect of both cyanide detoxification. This method has been successfully used in some patients with severe sulfide poisoning. Sulphide poisoning causes damage to the capacity of oxygen transport is unfounded. On the other hand, the apparent cyanosis of some victims of hydrogen sulfide poisoning suggests that airway obstruction in this condition is more common than is commonly recognized. Upper airway aspiration and oxygenation may be important adjuncts to patients who use sodium nitrite.