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尽管认识到滥用苯丙胶、可卡因或迷幻药可引起颅内出血（ICH）已有多年，但传统性认为是高血压性出血而不对基本血管异常作研究。作者认为滥用这些所谓“药物”是年青人ICH的最常见原因。有两篇报道用苯丙胺及迷幻药后出现动静脉畸形破裂。可卡因诱发ICH与脑血管造影异常间有相
Although it has been recognized for many years that intracranial hemorrhage (ICH) has been induced by the abuse of styrene-acrylic, cocaine or psychedelic drugs, it has traditionally been considered as hypertensive hemorrhage without a study of essential vascular abnormalities. The author believes that the abuse of these so-called “drugs” is the most common cause of young ICH. There are two reports of arteriovenous malformation rupture following amphetamine and psychedelic drugs. Cocaine-induced ICH and cerebral angiography between the phase