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对15例先天性食管裂孔疝和15例单纯性胃食管返流(GER)的患儿进行了胃、食管测压研究。结果:先天性食管裂孔疝合并GER的患儿食管下端括约肌(LES)压力及其与胃压差明显低于正常(P<0.05),术后仍有下降趋势。LES长度术后较术前延长。未合并CER的患儿术前LES压力与胃压差稍低于正常,术后压力明显下降,与正常组比较差异显著(P<0.05)。单纯性GER组LES压力及其与胃压差明显低于正常,而且年龄越小降低越明显,GER诱发试验80%出现阳性。提示食管裂孔疝所致的解剖因素改变并不是发生GER的主要原因,LES压力也并不是衡量LES机能的唯一指标,对GER患儿的测压诊断在结合LES压力,长度和GER诱发试验进行综合分析。
Gastric and esophageal manometry studies were performed in 15 children with congenital hiatal hernia and 15 with simple gastroesophageal reflux (GER). Results: The pressure of lower esophageal sphincter (LES) in children with congenital esophageal hiatal hernia complicated with GER was significantly lower than that of normal (P <0.05), and there was still a decreasing trend after operation. LES length longer than before surgery. The preoperative LES pressure and gastric pressure difference in children with uncombined CER were slightly lower than normal, postoperative pressure decreased significantly, compared with the normal group (P <0.05). In simple GER group, LES pressure and its difference with gastric pressure were significantly lower than normal, and the more obvious the lower the age, the more the GER induced test was positive 80%. Suggesting that changes in anatomic factors caused by hiatal hernia is not the main reason for the occurrence of GER, LES pressure is not the only measure of LES function of the indicators, the measurement of GER in children with pressure measurement in combination with LES pressure, length and GER-induced test synthesis analysis.