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患者女性63岁,5～6年前左大腿伸侧出现褐色小肿瘤,渐增大,无自觉症状,局部亦无外伤史。体检见左大腿伸侧有豆大淡褐色表面粗糙的疣状肿瘤,边缘部分色较深,无红晕,肿瘤切除后一年半无复发。病理检查见肿瘤上方有棘层肥厚及乳头瘤样增殖。增生细胞为鳞状细胞,胞浆染伊红色。肿瘤下方部分区域可见基底样细胞。在肿瘤巢内有鳞状样细胞组成的许多大小不等的圆形巢,类似表皮
The patients were 63 years old and had small brown tumors on their left thighs extending from 5 to 6 years ago. They gradually increased without symptoms and there was no history of trauma. On the physical examination, there was a large hazel-like, rough-surfaced, verrucous tumor on the left thigh, with darker edges and no blush. There was no recurrence after tumor resection for one and a half years. Pathological examination showed acanthosis hypertrophy and papilloma-like proliferation above the tumor. The proliferating cells were squamous cells and the cytoplasm stained red. Basal-like cells can be seen in some areas below the tumor. Numerous and unequal round nests of squamous cells in the tumor nest, similar to the epidermis