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作者对10例正常双胎妊娠做了血中17β雌二醇、雌三醇、孕酮的测定。10例孕妇皆为志愿受试者。于孕30周前应用X线造影或超声检查双胎做出诊断。产后核实胎儿均属足月,体重在2500克以上者。自孕30周起每周采母血标本一次。用肝素抗凝、取血后立即离心分出血浆放于-15℃被测。应用特异抗体进行放射免疫测定。每一标本同时测定两份。用Hotchkiss(1971)法测17β雌二醇;用改进了的Wilson(1973)方法测雌三醇;用Devilla法(1972)测孕酮。两份试验结果之间或与对照试验结果之间的差别系数皆小于15％。血浆中雌二醇与三醇自孕30周起逐渐上升,二者上升率是平行的。在34～36周之间上升最明显,
The author of 10 cases of normal twin pregnancy blood 17β-estradiol, estriol, progesterone determination. All 10 pregnant women were volunteers. Pregnancy 30 weeks before the application of X-ray or ultrasound to diagnose twins. Postpartum verification of the fetus are full-term, weighing more than 2500 grams. Maternal blood samples taken once a week from the 30th week of pregnancy. Anticoagulation with heparin, centrifuged immediately after the blood taken plasma was measured at -15 ℃. Specific antibodies were used for radioimmunoassay. Two samples were taken simultaneously for each specimen. 17β estradiol was measured using the Hotchkiss (1971) method; estriol was tested using the modified Wilson (1973) method; and progesterone was measured using the Devilla method (1972). The difference between the two test results or between control test results is less than 15%. Plasma estradiol and triol from the 30th week of pregnancy gradually increased, the rate of rise is parallel to the two. In the 34 to 36 weeks the most obvious rise,