目的 :观察氩激光视网膜光凝术治疗增殖前期和增殖期糖尿病视网膜病变 (diabeticretinopathy ,DR)疗效。方法 :对 70例 (118眼 ,其中增殖前期 2 5眼 ,增殖期 93眼 )DR病人 ,依病变程度分别行全视网膜光凝或次全视网膜光凝治疗。术后随访 1年 ,观察光凝后患者的视力、眼底及荧光血管造影变化 ,并进行分析和对比。结果 :光凝治疗后 10 2眼有效 ,总有效率为 86 4% ,其中增殖前期 2 3眼有效 ,有效率 92 % ,增殖期 79眼有效 ,有效率 85 % ,二者有显著差异 (P <0 0 1) ,治疗后 2 7眼视力提高 (2 3 % ) ;77眼视力不变 (65 % ) ;14眼视力下降 (12 % )。在治疗前有黄斑水肿的 62眼中 ,治疗后有 13眼黄斑水肿完全吸收 (2 1% ) ,40眼部分吸收 (64 5 % ) ,9眼不变 (14 5 % )。结论 :氩激光视网膜光凝术是治疗DR的有效手段。对其增殖前期应尽早发现及时进行光凝治疗 ,以阻止病情发展 ,保护视功能。 Objective: To observe the effect of argon laser photocoagulation on proliferative diabetic retinopathy (DR). Methods: Total retinal photocoagulation or subretinal photocoagulation was performed in 70 patients (118 eyes, 25 eyes in proliferative stage and 93 eyes in proliferative stage). The patients were followed up for 1 year. Visual acuity, fundus and fluorescein angiography were observed after photocoagulation, and analyzed and compared. Results: The total effective rate was 86.4% after the photocoagulation treatment, with a total effective rate of 86.4%, of which 23 were effective in pre-proliferative period, the effective rate was 92%, the proliferative period was 79 and the effective rate was 85%, both of which were significantly different (P <0 0 1). The visual acuity increased 27% (23%) after treatment; 77 eyes remained unchanged (65%); 14 eyes decreased vision (12%). Of the 62 eyes with macular edema before treatment, 13 had macular edema completely (21%), 40 partially absorbed (64 5%) and 9 unchanged (14 5%) after treatment. Conclusion: Argon laser photocoagulation is an effective treatment for DR. Proliferation of its early detection of phototherapy should be promptly found to prevent disease progression and protect visual function.