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本文采用ELISA法对25例慢性肝炎,105例肝硬化,64例肝癌,以及8例急性黄疸型肝炎进行了HBV标志物及抗-HCV的检测。结果:HBV感染率为80.6％,抗-HCV检测阳性率为46％,二者均阳性的双重感染率为32％。其中肝癌组双重感染明显高于肝硬化组,P<0.001。单纯抗-HCV检出率为10.8％。说明HBV是引起肝炎、肝硬化、肝癌的主要原因,而HCV感染也是其致病因素。本文对有输血史的慢性肝炎、肝硬化、肝癌100例进行抗-HCV检测其阳性率为59％,而102例无输血史的肝病患者抗-HCV检出率为25％,输血组抗-HCV检出率明显高于无输血组,P<0.001。其中慢性肝炎、肝硬化、肝癌病人输血组抗-HCV检出率亦明显高于无输血组,各组P<0.001,故提示,HCV感染与输血有密切关系。 50例HBV标志物阴性的健康献血员抗-HCV阳性率为6％。
In this paper, HBV markers and anti-HCV were detected by ELISA in 25 cases of chronic hepatitis, 105 cases of liver cirrhosis, 64 cases of liver cancer, and 8 cases of acute jaundice hepatitis. Results: The HBV infection rate was 80.6%, anti-HCV test positive rate was 46%, both were positive double infection rate was 32%. The double infection in HCC group was significantly higher than that in cirrhosis group, P <0.001. Simple anti-HCV detection rate of 10.8%. Description of HBV is caused by hepatitis, cirrhosis, liver cancer is the main reason, and HCV infection is also the causative factor. In this paper, the positive rate of anti-HCV in 100 cases of chronic hepatitis, cirrhosis and liver cancer with transfusion history was 59%, while the detection rate of anti-HCV was 102% in 102 cases of liver disease without transfusion history, The detection rate of HCV was significantly higher than that without blood transfusions (P <0.001). Among them, the detection rate of anti-HCV in transfusion group of patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma was also significantly higher than those without transfusion group, P <0.001 in each group, suggesting that HCV infection is closely related to blood transfusion. The positive rate of anti-HCV in 50 HBV-negative healthy blood donors was 6%.