论文部分内容阅读
目的:观察断藤益母汤对比常规用药对类风湿关节炎患者临床疗效.方法:选取2014年6月～ 2016年6月在本院专科门诊及住院治疗的226名类风湿关节炎患者.将226名患者按113人一组随机分为两组,试验组服用断藤益母汤;对照组服用来氟米特片.持续用药3个月后观察患者的关节肿胀关节数、压痛关节数、晨僵时间、患者对疼痛度和病情整体的VAS评分以及医生对患者病情的VAS评分、健康状况问卷(HAQ)临床症状指标的差别和血沉(ESR)、C-反应蛋白(CRP)以及类风湿因子(RF)指标的不同.结果:两组患者通过治疗都能达到很好的效果,试验组在关节肿胀关节数、压痛关节数、晨僵时间、患者对疼痛度和病情整体的VAS评分以及医生对患者病情的VAS评分、健康状况问卷(HAQ)的临床指标与对照组比较差异有统计学意义(P＜0.05);试验组在血沉(ESR)、C-反应蛋白(CRP)以及类风湿因子(RF)与对照组比较差异有统计学意义(P＜0.05).结论:断藤益母汤对类风湿关节炎患者具有改善关节活动功能及降低风湿炎症指标的作用,对比来氟米特改善关节以及降低指标的作用更明显.“,”Objective:To study the clinical effect of Duanmeng Yimu Decoction on patients with rheumatoid arthritis compared with routine medication.Methods:A total of 226 rheumatoid arthritis patients were selected from June 2014 to June 2016.226 patients were randomly divided into two groups according to a group of 113 people,the test group took Duanteng Yimu Decoction;the controlled group took Leflunomide Tablets.After 3 months of continuous medication,the number of joints,the number of tender joints,the time of morning stiffness,the VAS score of the pain and the overall condition of the patient and the VAS score of the patient's condition,the clinical symptom index of the health status questionnaire (HAQ) (ESR),C-reactive protein (CRP),and rheumatoid factor (RF).Results:The two groups of patients through the treatment could achieve good results,the experimental group in the joint swelling of the number of joints,the number of tender joints,morning stiffness,pain and the patient's overall VAS score and the doctor's VAS score on the patient's condition,health status.There was significant difference between the clinical indexes of the questionnaire (HAQ) and the controlled group (P ＜ 0.05).The ESR,C-reactive protein and rheumatoid factor (RF) in the experimental group were significantly higher than those in the controlled group (P ＜ 0.05).The difference was statistically significant.Conclusion:It can improve the function of arthritis and reduce the index of rheumatism in patients with rheumatoid arthritis.The effect of leflunomide on improving joint and reducing the index is more obvious.