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目的观察ω-3鱼油脂肪酸在ARDS的治疗中,对血气指标PaO2(mmHg)、PaO2/FiO2(mmHg)、血清白蛋白、APACHEⅡ评分的影响。方法将ARDS患者随机分为实验组和对照组,对照组采用基础治疗,实验组采用基础治疗上早期加用ω-3鱼油脂肪乳剂。结果实验组在6d后A-PACHEⅡ评分低于对照组,差异有统计学意义(P<0.05),血清白蛋白在第6天高于对照组,差异有统计学意义(P<0.05);实验组6d后血气指标PaO2(mmHg)PaO2/FiO2(mmHg)均高于对照组,差异有统计学意义(P均<0.05);实验组ω-3鱼油脂肪酸注射液未发现明显的不良反应。结论ω-3鱼油脂肪酸早期应用于ARDS可促进器官功能恢复,安全、有效。
Objective To observe the effects of omega-3 fish oil fatty acids on the blood gas indexes PaO2 (mmHg), PaO2 / FiO2 (mmHg), serum albumin, APACHEⅡscore in the treatment of ARDS. Methods ARDS patients were randomly divided into experimental group and control group. The control group received basic treatment. The experimental group was treated with omega-3 fish oil emulsion on the basis of early treatment. Results The score of A-PACHEⅡin the experimental group was lower than that in the control group after 6 days (P <0.05), serum albumin was higher on the 6th day than the control group (P <0.05) After 6 days, PaO2 (mmHg) PaO2 / FiO2 (mmHg) were higher than those of the control group (all P <0.05). No significant adverse reactions were found in the omega-3 fish oil fatty acid injection. Conclusion The early application of ω-3 fish oil fatty acid in ARDS can promote organ function recovery, which is safe and effective.