论文部分内容阅读
目的:探讨老十针防治顺铂化疗引起的消化道症状的临床应用效果。方法:选取2013年2月—2014年12月期间,医院所收治的接受以顺铂为主要化疗方案的癌症患者44例,随机将患者分为对照组和研究组,每组22例。对照组患者服用吗丁啉,研究组患者采用“老十针”针刺预防消化道症状。对两组患者临床治疗效果,治疗前后消化不良症状评分变化情况,KPS评分情况以及不良反应发生情况进行比较研究。结果:与对照组患者相比,研究组患者的临床痊愈率36.36%(8/22)和总有效率95.45%(21/22)均显著增加,而无效率4.55%(1/22)则显著降低,食欲不振、恶心呕吐化疗消化道症状发生率和评分明显降低,差异具有统计学意义(P<0.05),而味觉异常、口腔疼痛、吞咽不适、呃逆、胃胀胃痛、胃灼热、便秘以及腹泻等化疗消化道症状发生率和评分虽有所降低,但差异均不具有统计学意义(P>0.05)。讨论:老十针对顺铂引起的消化道症状起到有效的治疗作用,同时能够改善患者的身体状况,降低不良反应的发生。其可作为一种安全、有效的联合治疗方法应用于癌症患者的化疗方案。
Objective: To investigate the clinical effect of Lao Shizhen on prevention and treatment of gastrointestinal symptoms caused by cisplatin chemotherapy. Methods: From February 2013 to December 2014, 44 patients with cancer who received cisplatin as the main chemotherapy regimen were randomly divided into control group and study group, with 22 patients in each group. Control group patients taking domperidone, the study group patients with “old ten needles ” acupuncture to prevent gastrointestinal symptoms. The clinical efficacy of the two groups of patients, before and after treatment of dyspeptic symptoms score changes, KPS score and adverse reactions were compared. Results: Compared with the control group, the clinical cure rate and the total effective rate of 36.36% (8/22) and 95.45% (21/22) of the study group were significantly increased, while the inefficiency rate of 4.55% (1/22) was significantly The incidence and score of gastrointestinal symptoms such as decreased appetite, nausea and vomiting were significantly lower (P <0.05), while the abnormal taste, oral pain, swallowing discomfort, hiccups, stomachache, heartburn, constipation and Diarrhea and other chemotherapy, the incidence of gastrointestinal symptoms and score decreased, but the difference was not statistically significant (P> 0.05). DISCUSSION: Lao Xi is effective in treating gastrointestinal symptoms caused by cisplatin, meanwhile, it can improve the physical condition of patients and reduce the incidence of adverse reactions. It can be used as a safe and effective combination therapy for cancer patients with chemotherapy.