硝硫氰胺是抗血吸虫病的口服新药,近年已大批投产,并研制了各种不同剂型试用于临床。由于剂型选择不当可影响药物疗效,我们对四川医学院研制的本品微囊剂型进行了动物实验和临床观察,取得了满意效果。本剂型系采用邻苯二甲酸醋酸纤维素为囊材,将硝硫氰胺进行单凝聚包囊,再制成片剂。它既可防止微粉聚结,提高药物的稳定性,又可延缓药物释放。为了考查这种剂型在长期存放后疗效是否稳定.我们把同一批号的本品微囊片剂存放不同时间,在不同贮存条件下,再用于 Nitrocyanamine is an oral new anti-schistosomiasis medicine, in recent years has been a large number of production, and developed a variety of different dosage forms for clinical trial. Due to improper dosage forms can affect the efficacy of the drug, we developed the animal experiments and clinical observation of this product microcapsules formulation developed by Sichuan Medical College and achieved satisfactory results. The dosage form is made of cellulose acetate phthalate as a capsule material, and the nitrocyanine amine is condensed and encapsulated, and then made into a tablet. It can prevent powder coalescence, improve drug stability, but also delay the release of drugs. In order to examine the efficacy of this formulation after long-term storage is stable.We put the same batch of this product microcapsule tablets stored at different times, under different storage conditions, and then used in