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目的探讨不同方案治疗新诊断2型糖尿病的经济效益。方法59例新诊断2型糖尿病患者随机分成3组,A组19例,用格列吡嗪控释片5m g,qd,联合盐酸二甲双胍片0.5g,tid,疗程21d。B组20例,用格列吡嗪控释片5m g,qd,盐酸二甲双胍片0.5g,tid,联合精蛋白锌重组人胰岛素注射液睡前皮下注射0.1u.kg-1体重,疗程21d。C组20例,即胰岛素强化治疗方案。早餐皮下注射精蛋白锌重组人胰岛素混合注射液,晚餐皮下注射重组人胰岛素注射液,睡前皮下注射精蛋白锌重组人胰岛素注射液,疗程21d。运用成本-效果分析进行评价。结果A、B、C组的成本-效果比分别为:5.25、5.09、4.40。C方案为最佳治疗方案。
Objective To explore the economic benefits of different regimens in the treatment of newly diagnosed type 2 diabetes. Methods Fifty-nine newly diagnosed type 2 diabetic patients were randomly divided into three groups. Group A received 19 g of glipizide 5 g g qd and metformin hydrochloride 0.5 g tid for 21 d. B group 20 cases, with glipizide controlled release tablets 5m g, qd, metformin hydrochloride tablets 0.5g, tid, combined with protamine zinc recombinant human insulin injection before bedtime injection 0.1u.kg-1 weight, treatment 21d. C group of 20 cases, that is, insulin intensive treatment program. Breakfast subcutaneous injection of protamine zinc recombinant human insulin injection, dinner subcutaneous injection of recombinant human insulin injection, bedtime subcutaneous injection of protamine zinc recombinant human insulin injection, treatment 21d. Use cost-effectiveness analysis to evaluate. Results The cost-effectiveness ratios of group A, B and C were 5.25, 5.09 and 4.40 respectively. C program for the best treatment.