去甲乌药碱恒速输注每分5μg/kg,10μg/kg能明显降低家兔肾血流量。5μg/kg输注至30分钟,尿中钠排泄减少50％,而对尿量和钾的排泄无明显影响。10μg/kg输注15分钟,使乌拉坦或戊巴比妥钠麻醉,不同水负荷量家兔的尿量和钠排泄明显降低,对钾的排泄无明显影响。 Intravenous infusion of azarubine at a rate of 5μg/kg per minute, 10μg/kg can significantly reduce renal blood flow in rabbits. At 5 μg/kg infusion for 30 minutes, urinary sodium excretion was reduced by 50%, but there was no significant effect on urine output and potassium excretion. At 15 μg/kg infusion for 15 minutes, urethane or pentobarbital was anesthetized. The urine output and sodium excretion of rabbits with different water load were significantly reduced, and there was no significant effect on potassium excretion.