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本文报道了我院1978年前1238例脑肿瘤中12例颅内生殖细胞性肿瘤的病理形态特征。12例中生殖细胞瘤7例,恶性畸胎瘤3例,生殖细胞瘤与恶性畸胎瘤混合者1例,胚胎性癌1例。12例中除1例在松果体部可见到肿瘤外,其余均不在松果体部位,形态上也与性生殖细胞瘤一致,作者认为称生殖细胞瘤概念更明确。其分类同意分为生殖细胞瘤、畸胎瘤、绒毛膜癌、胚胎性癌四型,但作者认为还应根据肿瘤成分、分化方向及混合存在的情况再分别归类,这样更有利于探讨各种类型的生物学行为,予后和最合适的治疗方法。作者还就鉴别诊断等方面进行了讨论。
This article reports 12 cases of brain tumors in our hospital before 1978, 12 cases of intracranial germ cell tumors of the pathological features. 7 cases of germ cell tumor in 12 cases, 3 cases of malignant teratoma, 1 case of mixed germ cell tumor and malignant teratoma and 1 case of embryonal carcinoma. 12 cases in addition to a case in the pineal body can be seen in the tumor, the rest are not in the pineal region, morphologically consistent with germ cell tumors, the authors believe that the concept of germ cell tumor more clearly. The classification agreed to be divided into germ cell tumors, teratoma, choriocarcinoma, embryonal carcinoma type four, but the authors believe that should be based on tumor composition, differentiation and mixed presence of the case were then re-classified, it is more conducive to explore each Kinds of biological behavior, post-treatment and the most appropriate treatment. The author also discussed the differential diagnosis and other aspects.