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目的 观察静脉滴注胺碘酮在急性心肌梗死 (AMI)伴快速房颤患者临床疗效。方法 19例AMI患者伴新近发生快速房颤 ,静脉应用胺碘酮 ,静脉负荷量后 ,继以静点维持观察房颤转复及心室率控制及副作用。结果 19例患者用药后 15min ,1h ,2h ,2 4h心室率分别为 (132 1± 17 4)次 分 ;(118 5± 15 0 )次 分 ;(10 8 2± 18 6 )次 分 ;(89 6± 2 3 7)次 分 ,较用药前 (149 7± 19 7)次 分明显下降。其中 14例患者 (73 6 % )在 2 4h内转为窦性心律 ,3例患者用药后出现长间歇 ,1例出现窦缓 ,经临时停药或减量后恢复。结论 静脉应用胺碘酮治疗AMI并发的快速房颤是有效及安全的
Objective To observe the clinical effect of intravenous drip amiodarone in patients with acute myocardial infarction (AMI) accompanied by rapid atrial fibrillation. Methods Nineteen patients with acute myocardial infarction (AMI) accompanied by recent rapid atrial fibrillation were treated with intravenous amiodarone and venous load, followed by intravenous maintenance of atrial fibrillation and ventricular rate control and side effects. Results In 19 patients, the ventricular rates at 15 min, 1 h, 2 h, and 24 h were (132 1 ± 17 4) times, (118 5 ± 15 0) times, (10 8 2 ± 18 6) 89 6 ± 2 3 7) times, significantly lower than that before treatment (149 7 ± 19 7) times. Among them, 14 patients (73.6%) were converted to sinus rhythm within 24 hours. Three patients experienced long-term intermittent dosing and sinus rhythm in one case, and were recovered after temporary withdrawal or reduction. Conclusion Intravenous amiodarone is effective and safe in the treatment of AMI complicated with rapid AF