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目的 :探讨热性惊厥 (FC)时异常脑电图 (EEG)与以后癫的发作 ,与FC的再发及预防性治疗的关系。方法 :记录 186例 4 6岁患儿FC后EEG。结果 :首次EEG异常率为 33 % ;EEG异常率与Ⅰ级亲属的热惊厥史无关系 ;EEG异常率与FC临床特征 (局灶性发作和FC持续时间 >15分钟 )有关 ;首次FC的EEG异常率为 12 % ,随着FC再发次数的增多逐渐增高 ,FC再发 3次以上的患儿中 ,其EEG异常率高达 35 8%～ 5 3 3% ;3岁以内FC儿其EEG异常率不明显 ,3岁以后的FC儿EEG的异常率则逐渐增多 ,有统计意义 ;部分患儿多次EEG检查出现发作性棘波 ,其中 3例随访 4～ 8年 ,最后诊断为癫。结论 :EEG异常率与Ⅰ级亲属是否有FC史无关 ,与FC临床特征有关系 ;FC再发与EEG异常、年龄有明显关系 ;EEG多次异常FC可发展为癫 ;建议预防性治疗。
Objective: To investigate the relationship between abnormal electroencephalogram (EEG) and subsequent epileptic seizures in patients with febrile seizures (FC) and the relapse and prophylactic treatment of FC. Methods: The EEG of 186 children aged 4-6 years were recorded. Results: The abnormal rate of EEG for the first time was 33%. The abnormal rate of EEG was not related to the history of febrile seizures in the first degree relatives. The EEG abnormality rate was related to the clinical features of FC (focal episodes and FC duration> 15 minutes) The abnormal rate was 12%. With the increase of FC recurrence, the abnormal EEG rate was 35.8% ~ 53.3% in children with FC recurrence more than 3 times. The rate of abnormal EEG in FC children after 3 years of age increased gradually, which was statistically significant. Some of the children had episodes of Echocardiography with multiple EEG tests. Among them, 3 cases were followed up for 4 to 8 years and finally diagnosed as epilepsy. CONCLUSIONS: The abnormal rate of EEG has nothing to do with the history of FC in the first degree relatives, which is related to the clinical features of FC. The recurrence of FC is related to the EEG abnormalities and age. EEG multiple abnormalities FC can develop into epilepsy. Preventive treatment is recommended.