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目的:临床中不典型增生的胃粘膜形态变化分析。方法:2008年~2012年我院接收5282例内镜检查患者,对这些患者的资料进行分析研究不典型增生和胃粘膜形态变化之间的关系。结果:典型增生的内镜检出率2.4%。不同年龄组间检出率比较差异有显著性(p<0.05)。胃镜下不同黏膜形态不典型增生的内镜检出率不同,差异有显著性(p<0.05)。不典型增生在溃疡、大结节(>5 mm)顶端无糜烂或溃疡、大结节顶端糜烂或溃疡3种形态下内镜检出率较高,均超过5%。结论:不典型增生与胃粘膜形态变化之间存在着相关性,为了获得更好的内镜检出率,可以在粘膜形态变化的部位进行取材。
Objective: To analyze the morphological changes of gastric mucosa in patients with atypical hyperplasia in clinic. Methods: From 2008 to 2012, 5282 cases of endoscopy were received in our hospital. The data of these patients were analyzed to study the relationship between dysplasia and gastric mucosal changes. Results: The endoscopic detection rate of typical hyperplasia was 2.4%. The detection rate of different age groups was significantly different (p <0.05). Endoscopic detection rate of different mucosal atypical hyperplasia under gastroscope was different, the difference was significant (p <0.05). Atypical hyperplasia in the ulcer, large nodules (> 5 mm) no erosion or ulceration at the top, the top of the large nodules or erosion of the three endoscopic detection rate was higher, more than 5%. CONCLUSIONS: There is a correlation between dysplasia and gastric mucosa morphological changes. In order to obtain a better detection rate of endoscopy, mucosal morphological changes can be taken from the site.