甲氧苄氨嘧啶简称 TMP,是一种广谱抗菌药,其抗菌谱与磺胺嘧啶类似.但对链球菌及大多数革兰氏阴性杆菌的抗菌作用比磺胺嘧啶强。对耐 SD(磺胺嘧啶),SMZ(磺胺甲基异恶唑)的菌株也有显著的抗菌作用。它与磺胺药联合应用如 SMZ、SD、SMD(磺胺甲氧嘧啶)、SMPZ(磺胺—3—甲氧吡嗪)等,可阻断细菌的叶酸代谢,使磺胺类的抑菌作 Trimethoprim, abbreviated as TMP, is a broad-spectrum antimicrobial drug whose antibacterial spectrum is similar to sulfadiazine but which is more potent against sulfadiazine than streptococcus and most gram-negative bacilli. On SD (sulfadiazine), SMZ (sulfamethoxazole) strains also have significant antibacterial effect. It is used in combination with sulfa drugs such as SMZ, SD, SMD (sulfamethoxine), SMPZ (sulfa-3-methoxy pyrazine), etc., can block the folic acid metabolism of bacteria, so sulfa antibacterial