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目的探讨乳酸左氧氟沙星(LVLXL)注射液用于细菌性感染疾病的临床效果及不良反应。方法选取2012年1月~2012年12月128例由于细菌性感染前来本院就诊患者的为研究对象,随机将患者分为观察组及对照组,每组各64例患者,其中观察组患者应用乳酸左氧氟沙星注射液进行治疗,对照组患者应用氧氟沙星注射液进行治疗,两组患者注射剂量均为0.6g/d,疗程为5~7d。结果观察组患者治愈率及总有效率分别为70.31%和95.31%,对照组患者分别为53.13%和79.69%;观察组不良反应率为12.5%,对照组不良反应率为23.44%。单项不良反应比较,观察组输液部位起红线发生率显著低于对照组,差异有统计学意义(P<0.05)。与对照组相比,观察组患者临床治愈率及总有效率较高,不良反应发生率较低。结论对细菌性感染患者应用乳酸左氧氟沙星注射液治疗具有安全、有效、不良反应率较低等优点,值得临床上应用。
Objective To investigate the clinical effects and adverse reactions of levofloxacin lactate injection for bacterial infections. Methods From January 2012 to December 2012, 128 patients who came to our hospital due to bacterial infection were selected as study subjects. Patients were randomly divided into observation group and control group, with 64 patients in each group. Patients in observation group Application of levofloxacin lactate injection for treatment, the control group of patients treated with ofloxacin injection, the two groups were injected with a dose of 0.6g / d, treatment for 5 ~ 7d. Results The cure rate and total effective rate were 70.31% and 95.31% in the observation group and 53.13% and 79.69% in the control group respectively. The adverse reaction rate in the observation group was 12.5% and that in the control group was 23.44%. Compared with the single adverse reaction, the incidence of red line in the infusion site of the observation group was significantly lower than that of the control group (P <0.05). Compared with the control group, the observation group patients clinical cure rate and total effective rate is higher, the incidence of adverse reactions is lower. Conclusion The application of levofloxacin lactate injection in patients with bacterial infection is safe, effective and has a low adverse reaction rate, which is worthy of clinical application.