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目的观察星状神经节阻滞配合补佳乐治疗女性更年期综合征的临床效果。方法选择年龄在40～64岁更年期或手术绝经后有绝经相关症状的患者64例,按就诊顺序将患者随机分为2组,每组32例。Ⅰ组采用星状神经节阻滞配合口服补佳乐治疗,Ⅱ组采用单纯口服补佳乐治疗。所有患者在治疗前及Ⅰ组患者完成第2疗程星状神经节阻滞1周后的相同时间观察治疗前后绝经症状变化(kuppernann评分)。结果Ⅰ组与Ⅱ组治疗后kuppernann评分与治疗前比较差异有统计学意义(P<0.01或P<0.05)。Ⅰ组与Ⅱ组治疗后kuppernann评分比较差异有统计学意义(P<0.05)。结论星状神经节阻滞配合补佳乐能有效控制和改善女性更年期综合征患者症状,较单独应用激素替代治疗(HRT)效果更佳。
Objective To observe the clinical effect of stellate ganglion blockade and nadrogol on female climacteric syndrome. Methods Sixty-four patients with menopause-related menopause or menopause-related symptoms after 40-64 years of age were selected. Patients were randomly divided into two groups (n = 32 in each group). In group I, stellate ganglion block was used in combination with oral gavage, and in group II, oral gavage alone was used. All patients underwent pre-treatment and post-treatment changes in menopausal symptoms (kuppernann score) before treatment and at 1 week after completion of the second course stellate ganglion block in group I patients. Results The kuppernann score of group Ⅰ and group Ⅱ after treatment was significantly different from that before treatment (P <0.01 or P <0.05). The difference of kuppernann score between group Ⅰ and group Ⅱ was statistically significant (P <0.05). Conclusions Stellate ganglion blockade combined with nadrogol can effectively control and improve the symptoms of female climacteric syndrome patients, which is better than hormone replacement therapy (HRT) alone.