自Khler和Milstein创建单克隆抗体(McAb)技术以来.该技术不断发展完善,其应用亦日益广泛。人黄体生成素(hLH)是脑垂体前叶促性腺细胞分泌的一种糖蛋白激素,是调节男女生殖机能的重要物质。目前,国外一些实验室已建成了hLH的单克隆抗体细胞株,并应用于临床诊断,但国内尚未见报道。本研究旨在建立自己的hLH McAb细胞株,以满足国内临床和计划生育科研工作的需要。 Since the creation of monoclonal antibodies (McAb) by Köhler and Milstein, the technology continues to evolve and become more widely used. Human luteinizing hormone (hLH) is a glycoprotein hormone secreted by the gonadal cells of the anterior pituitary gland. It is an important substance that regulates the reproductive function of men and women. At present, some foreign laboratories have built hLH monoclonal antibody cell lines, and used in clinical diagnosis, but has not been reported in China. This study aims to establish our own hLH McAb cell line to meet the needs of domestic clinical and family planning scientific research.