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应用放射免疫分析法,测定了113例活动性肝炎后肝硬化患者血清透明质酸(HA),包括36例住院期间死亡的病人及77例好转出院者。其中男98例,死亡34例,女15例,死亡2例,年龄5～60岁。36例死亡病例主要死因为肝功能衰竭12例,上消化道出血9例,肝性脑病、肝肾综合征、腹腔感染各5例。检测结果,肝硬化病死组血清HA 测定值683.14±207.66μg/L,好转组HA 测定值405.85±236.22μg/L,病死组血清HA 明显高于好转组(P<0.001)。对113例肝硬化患者进行Child 分级。Child A 级26例,血清HA 测定
Using radioimmunoassay, serum hyaluronic acid (HA) was measured in 113 patients with active cirrhosis, including 36 patients who died during hospitalization and 77 patients who were discharged. There were 98 males, 34 died, 15 females, and 2 died, ranging in age from 5 to 60 years. The main causes of death in 36 cases were 12 cases of liver failure, 9 cases of upper gastrointestinal bleeding, hepatic encephalopathy, hepatorenal syndrome and 5 cases of intra-abdominal infection. The results showed that the serum HA was 683.14 ± 207.66μg / L in the cirrhosis group and 405.85 ± 236.22μg / L in the HA group. The serum HA level in the deceased group was significantly higher than that in the control group (P <0.001). 113 patients with cirrhosis were stratified by Child. Child A grade 26 cases, serum HA determination