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目的 :利用标记免疫分析CA19-9、CA72 -4、CEA、AFP水平进行对食道癌、胃癌、肝癌、小肠癌、大肠癌、胰腺癌和胆囊癌的诊断研究。方法 :标记免疫分析了确诊食管癌 6例、胃癌 13例、肝癌 2 1例、空肠癌 2例、大肠癌 13例、胰腺癌 5例和胆囊癌 1例 ,并比较单项检测和联合检测的意义。结果 :4种肿瘤标记物中以CA19-9敏感性最高达 92 %,特异性以AFP最高达 86%,联合检测可提高其敏感性达 81%。结论 :肿瘤标记物联合检测有助于提高消化系恶性肿瘤诊断率
OBJECTIVE: To study the diagnosis of esophageal cancer, gastric cancer, liver cancer, small intestine cancer, colorectal cancer, pancreatic cancer and gallbladder cancer by using labeled immunoassay CA19-9, CA72-4, CEA and AFP. Methods: Six cases of esophageal cancer, 13 cases of gastric cancer, 21 cases of hepatoma, 2 cases of jejunal carcinoma, 13 cases of colorectal carcinoma, 5 cases of pancreatic carcinoma and 1 case of gallbladder carcinoma were identified by immunohistochemistry. The significance of single detection and combined detection was compared . Results: The sensitivity of CA19-9 was up to 92%, the specificity of AFP was up to 86%, and the sensitivity of combined detection was 81%. Conclusion: Combined detection of tumor markers can help improve the diagnosis of digestive malignancies