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目的:探讨急性上消化道大出血患者的心电图和心肌损害标志物(肌钙蛋白、肌酸激酶同工酶、肌红蛋白)的动态改变及其临床意义。方法:对急性上消化道大出血患者的心电图及心肌损害标志物分别于第1天、第10天进行检测并作数据分析。结果:上消化道大出血患者起病后第1天心电图均出现异常,心肌损害标志物大部分都有程度不等的升高,10 d后随着病情缓解异常变化的比例明显减少。结论:急性上消化道大出血患者大部分易并发心肌损害,因此要加强心脏监护,抢救时应兼顾心脏情况。
Objective: To investigate the dynamic changes of ECG and myocardial damage markers (troponin, creatine kinase isoenzyme, myoglobin) in patients with acute upper gastrointestinal bleeding and its clinical significance. Methods: Electrocardiogram and myocardial damage markers in patients with acute upper gastrointestinal bleeding were detected on day 1 and day 10, respectively, and analyzed for data. Results: On the first day after onset of upper gastrointestinal bleeding, the electrocardiogram showed abnormalities. Most of the markers of myocardial damage increased to varying degrees. After 10 days, the proportion of patients with abnormal changes of mitochondrial dysfunction was significantly decreased. Conclusion: Most patients with acute upper gastrointestinal bleeding are prone to complicated with myocardial damage, so heart monitoring should be strengthened.