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很久就认为下丘脑是调节食欲的中枢。近十年来对单胺及肽类神经介质调节进食的作用进行了大量的工作。本文着重介绍胺肽对大鼠进食的影响和食欲中枢的解剖学。 一、下丘脑进食中枢的解剖部位 对食欲的主要调节区域是在下丘脑,发现有两个中枢:一个是在下丘脑腹外侧区(VLH),它是中枢神经系统的主要进食中枢。电刺激此区可引起饱食动物进食,破坏此区则动物拒食。另一个中枢是下丘脑的腹内侧区(VMH),它是饱觉中枢。电刺激
Long considered hypothalamus is the central regulator of appetite. In the past decade, a great deal of work has been done on the regulation of monoamine and peptide nerve mediators. This article highlights the effects of amine peptides on food intake in rats and the anatomy of the appetite center. First, the anatomical site of the hypothalamic feeding center is the main regulatory area of appetite in the hypothalamus, found that there are two centers: one in the hypothalamic ventrolateral region (VLH), which is the central feeding center of the central nervous system. Electrical stimulation of this area can cause satiety animals to eat, destroy the area of animal antifeedant. The other hub is the ventromedial region of the hypothalamus (VMH), which is the saturating center. Electrical stimulation